EMAPII

With Matthias Clauss, PhD, we study the mechanistic link between apoptosis and inflammation in the lung via the cytokine EMAPII.

Selected related publications

  • Green, L. A. et al. HIV envelope protein gp120-induced apoptosis in lung microvascular endothelial cells by concerted upregulation of EMAP II and its receptor, CXCR3. American journal of physiology. Lung cellular and molecular physiology 306, L372-382, doi:10.1152/ajplung.00193.2013 (2014).
  • Green, L. A. et al. Cigarette smoke-induced CXCR3 receptor up-regulation mediates endothelial apoptosis. American journal of respiratory cell and molecular biology 47, 807-814, doi:10.1165/rcmb.2012-0132OC (2012).
  • Clauss, M. et al. Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice. The Journal of clinical investigation 121, 2470-2479, doi:10.1172/jci43881 (2011).
  • Rajashekhar, G. et al. A monoclonal rat anti-mouse EMAP II antibody that functionally neutralizes pro- and mature-EMAP II in vitro. Journal of immunological methods 350, 22-28, doi:10.1016/j.jim.2009.08.003 (2009).
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